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Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli, despite adverse consequences.[8] Despite the involvement of a number of psychosocial factors, a biological process ,– one which is induced by repeated exposure to an addictive stimulus ,– is the core pathology that drives the development and maintenance of an addiction.[9] The two properties that characterize all addictive stimuli are that they are reinforcing (i.e., they increase theAddiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc.).[10][11] ΔFosB, a gene transcription factor, is a criti Toggle News



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